Oxycodone is an analgesic (pain-killer), which works by affecting the central nervous system. Oxycodone generally causes opiate-like effects when used. It is equal to morphine in analgesic effects and also in relieving self-restraint symptoms from chronic opiate (heroin, morphine) use. Oxycodone’s behavioral effects can last up to 5 hours. The continuous-release formula has a longer duration of affect (8-12 hours). In a study it is revealed that Oxycontin was twice as potent as MS Contin for causing Opiate effects. Oxycodone is a potentially addictive opioid analgesic medicine and Schedule II controlled substance synthesized from opium alkaloid thebaine. It is a strongly controlled substance that have a commonly accepted medical use such as medication for treatment of pain in cancer patients.
Why Oxycodone is Tested Separately
Oxycodones (Percodan, Percocet, Roxicodone and Oxycontin) are synthetically manufactured opiates and they are not directly refined from the opium poppy resin source. The chemical structure of Oxycodone requires a separate test with a substantially higher detection levels than that of the regular Opiate drug test. Consequently, a positive test result will not only confirm Oxycodone but other opiates as well. The 2000 ng/ml detection level of the regular opiate test would not detect Oxycodone. Here, Oxycodone test is not Oxycodone specific but opiate specific.
The Oxycodone Test
Oxycodone Test uses a unique method of monoclonal antibodies to identify Oxycodone and it’s metabolites in urine. Oxycodone Test technology incorporates a chromatographic absorbent device. The drug or drug metabolites in the urine sample compete with an opiate derivative on a porous membrane for limited antibody sites. This is the preferred scientific method for qualitative assay. In the assay procedure, urine mixes with labeled antibody-dye conjugate and gives the test results.
This assay can be considered as only a preliminary analytical test result. In the case of a positive result more specific tests should be conducted on the sample to confirm the result. For this, more specific alternative chemical method such as high-pressure liquid chromatography (HPLC) or gas chromatography/mass spectrometry (GC/MS) must be used in order to obtain a confirmed analytical result.
This information about the Oxycodone and its metabolites and the Oxycodone drug test will help you in understanding about the Oxycodones.
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Oxycodone Drug Test
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Benefits of Clia Waived Drug Tests
CLIA (Clinical Laboratory Improvement Amendment) Act was established in 1988 to set high quality laboratory testing methods to ensure accurate, reliable, timely test results etc. CLIA has categorized laboratory testing based on the test complexity of the performance and as per requirement of the laboratories. Waived drug test is one of the categorized laboratories testing with fulfillment of above requirements of the Act. Simple laboratory examination and procedures that are cleared by FDA for home use is known as waived drug test and mainly used to conduct preliminary or initial drug test.
Benefits of CLIA Waived Drug Test
Organizations provide various waived drug testing kits with 18 months durability from date of manufacturing and to be stored at room temperature. CLIA waived drug test uses simple and accurate methodologies to render appropriate test results without any risk of inconvenience for the patients. Many people are getting benefited with use this drug test like detection of drugs and few benefits are discussed below.
• Detects up to 12 drugs at a time: 12 drugs can be detected with help of 12 panel CLIA waived drug testing kit at a time. Amphetamine, Barbiturates, Benzodiazepines, Cocaine, Ecstasy, Marijuana, Methadone, Methamphetamine, Morphine, Opiates, Oxycodone and Phencyclidine are the drugs that can be detectable using this drug test. SAMHSA cutoff levels are used to detect the above drugs.
• Results are known in minutes: Results of test are known within 5 minutes and results are stable for 8 hrs from the time of performing the test. High quality standards with different methods of performing this test.
• Small quantity of specimen: This test can be performed on different specimens as per the kits available like urine, hair, blood etc. specimen collected for conducting these are about 3 ml. No extensive paper is required for sample collection and for conducting the test. There is no chance of specimen tampering or adulterating.
• Simple procedure: Very easy and simple procedure is followed for collection of specimen and performing the drug test. In hospitals, laboratories and at home this test is used very commonly, specified person is required for conducting these tests.
Accurate results: This test ensures accuracy, reliability and timeliness among the testing results. The main objective of CLIA is to provide quality laboratory testing results. These drug testing kits are approved by FDA.
Waived drug tests are affordable and fine effective, can be used at home, laboratories and hospitals. It helps you to test on your own to find any drug levels in your body or in your family members. The above points give you necessary information about CLIA waived drug test, procedure and benefits.
Drug Testing For Opiate
Opiates are one of the most addictive drugs with analgesic and sedative effects. According to TEDS report 2007, opiates accounted for almost one-fifth (19 %) of all substance abuse treatment admissions. Opiates include heroin, methadone, Oxycodone, Hydrocodone, Codeine, Dilaudid, Morphine, Demerol, Opium and other drugs that have Morphine like effects. The widespread abuse of Opiates stresses on the easy and quick drug testing process that gives instant results that help to check the abuse immediately.
One-step Opiate test is a preferred method to detect the Opiate and its metabolites in urine, as it is a simple to administer dip and read test. The cut off concentration for the test is 2000 mg/mL. that is approved by SAMHSA.
Sample collection:
The urine specimen should be collected in a dry and clean container. Urine collected at any time of the day can be used for the test. Specimens can be stored for up to 48 hours prior to testing at 2-8°C. Specimens with visible particles should be centrifuged, filtered or allowed to settle to obtain a clear specimen to test.
How to take the test:
Prior to testing, allow the specimen and test card to reach the room temperature. Remove the test card from the pouch and discard the small moisture absorbent packet. Immerse the test strip vertically in the urine specimen for 10 to 15 seconds, with arrows pointing towards the urine. Then place the test card on a non-absorbent flat surface and start the timer. Consider the results after 5 minutes of the test.
Interpretation of the test:
For a positive result, a red line appears in the control (C) region and no line appears in the test (T) region. For a negative result, a red line appears in the control (C) region and a red or pink line in the test (T) region. Control (C) line fails to appear for an invalid result. This may happen due to the insufficient specimen volume or incorrect procedural techniques.
This test card provides preliminary analytical test result. More specific chemical methods such as Gas chromatography/mass spectrometry (GC/MS) should be used to get confirmed analytical result, particularly after positive result in preliminary analytical test.
Opiate abuse continues to be a serious concern to public health. Therefore, drug abusers must be detected using effective drug tests like One-Step Opiate Test Strip. These tests are 95% to 98% accurate, FDA approved and provide results within minutes.
